微RNA研究助攻腦癌治療 獲85萬資助

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微小RNA研究計劃獲得加拿大腦癌協會85,000美元資助
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2025年5月5日 10:00 ET  | 來源:加拿大腦癌協會

多倫多,2025年5月5日(GLOBE NEWSWIRE)—— 加拿大腦癌協會欣然宣布,為多倫多大學的萊昂納多·薩爾梅納博士主導的一項前沿研究計劃提供85,000美元的資助。該項目名為“_探索微小RNA作為膠質母細胞瘤療法的靶點_”,旨在開發新穎的治療策略,以應對這種最具侵襲性和治療抵抗性的腦癌之一。

膠質母細胞瘤(GBM)是成年人中最常見且致命的腦腫瘤,診斷後五年內存活的患者不足5%。目前的治療方法大多無效,部分原因是存在一類被稱為膠質母細胞瘤幹細胞(GSCs)的細胞,這些細胞被認為驅動腫瘤的生長和對治療的抵抗。儘管這些細胞的重要性不言而喻,但對GSC生物學的理解仍存在顯著的空白。

薩爾梅納博士的研究旨在識別和表徵關鍵的微小RNA,這些小型非編碼的基因表達調節因子對GSC的生長和存活至關重要。他解釋道:“_我們的研究專注於揭示被稱為GSC的關鍵驅動細胞的生物學和脆弱性。只有深入理解這些細胞,我們才能希望開發出有效針對並消滅它們的創新療法。”_

他的團隊已經識別出幾種對這些過程至關重要的微小RNA,並正在調查它們在調節GSC行為中的具體作用。通過針對這些微小RNA,研究人員希望開發出能克服治療抵抗的新療法,最終改善GBM患者的生存結果。

這項工作代表了該領域的一個重要進展,為更有效的治療這種毀滅性疾病提供了一條有希望的道路。

“我為我們團隊在推進這個項目方面的努力感到非常自豪。我們真的相信這可能改變我們對GBM的看法和治療方式,”薩爾梅納博士說。“我們非常感謝加拿大腦癌協會以及來自全國各地的基層募捐者的非凡貢獻,使這筆資助成為可能,包括:為Jayne奔跑、推廣GBM的活動、為Don騎行、朱莉亞·科伊紀念活動以及為抗爭而戰的Farands。”

這一公告是加拿大腦癌意識月期間宣布的六項資助之一。加拿大腦癌協會仍然致力於推動創新解決方案,並為受腦癌影響的人士追求希望,投資於迫切需要的研究。

關於加拿大腦癌協會:
加拿大腦癌協會是一個全國性慈善機構,致力於改善受原發性惡性腦腫瘤影響的人的生活,通過資助研究、倡導有效的治療選擇和投資於神經外科技術。自2015年以來,加拿大腦癌協會已經為腦癌研究提供了超過240萬美元的資金,支持了25個項目,涵蓋全國九個機構、研究中心和醫院。

更多信息:
有關這項和其他由加拿大腦癌協會支持的研究計劃的詳細信息,請訪問[www.braincancercanada.ca](https://braincancercanada.ca/)

這項研究的資助不僅是對科學研究的支持,更是對無數腦癌患者及其家庭的希望。膠質母細胞瘤的治療一直以來都是醫學界的一大挑戰,這項研究專注於微小RNA的探索,或許能為未來的療法開辟新方向。隨著對GSC的深入了解,未來可能會出現更具針對性的治療方案,這不僅能提高患者的生存率,還能改善他們的生活質量。這樣的研究需要社會各界的支持,而加拿大腦癌協會的努力正是這種支持的體現。希望透過這些資助,能夠吸引更多的資源投入到腦癌的研究中,最終實現攻克這一疾病的目標。

以上文章由特價GPT API KEY所翻譯及撰寫。而圖片則由FLUX根據內容自動生成。

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